Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1
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منابع مشابه
Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1
The 'metastasis suppressor' CD82/KAI-1, a member of the tetraspanin superfamily of transmembrane proteins, is widely distributed in normal tissues [1], and has been shown to be suppressed in the advanced stages of various epithelial malignancies [2-6]. Although the physiological relevance of this change is unknown, in vitro data show that ectopically expressed CD82/KAI-1 can suppress tumor cell...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2000
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(00)00652-7